This peptide has been isolated from the bovine central nervous system, which implicated in a variety of physiological functions, including nociception, cardiovascular responses, and neuroendocrine regulation.
溶解度
分子量
746
化学式
C38H63N7O8
存储条件
Store at -20°C. Keep tightly closed. Store in a cool dry place.
A neuromedin U-related neuropeptide specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. rNMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. rNMS showed potent anorexigenic effects and counteracted neuropeptide Y, ghrelin and agouti-related protein-induced food intake. This compound is distributed through Peptide Institute, Inc. under the license of National Cardiovascular Center and Takeda Pharmaceutical Company Limited
溶解度
分子量
3791.34
化学式
C173H265N53O44
存储条件
Store at -20°C. Keep tightly closed. Store in a cool dry place.
Neuropeptide widely distributed in the gut and central nervous system that induces uterine contractile activity and may be a physiology regulator of food intake. IC50 values for the binding of neuromedin U-25 (human) to the human neuromedin U receptors NMU1R and NMU2R are 2.7nM and 1.8nM, respectively.
溶解度
分子量
4241.98
化学式
C193H307N57O49S1
存储条件
Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference
T.Ida et al., Endocrinology, 146, 4217 (2005) K.Mori et al., EMBO J., 24, 325 (2005)
Endogenous neurotensin-like neuropeptide from porcine spinal cord that exhibits contractile activity on guinea-pig ileum and induces hypotension in rats. It also acts as a potent modulator of dopamine D2 receptor agonist binding.
溶解度
分子量
2643
化学式
C124H180N34O31
存储条件
Store at -20°C. Keep tightly closed. Store in a cool dry place.