Moradec Fab-αHFc-NC-MMAF说明书
Moradec LLC由Helen（Hongyuan）Mao博士于2012年创立，主要目标是为快速和经济的抗体 – 药物结合物发现提供新颖的研究工具。毛博士拥有超过14年的工业研发经验，包括主要制药公司，中小型生物技术公司。她近担任Fabrus的科学官，这是开发Fabrus Arrayed抗体筛选技术的关键。除了广泛的抗体优化专业知识外，她还积累了基于表皮生长因子受体的抗体治疗方法的丰富知识。在Fabrus之前，Mao博士领导了Biosite（现为Alere）抗体开发的蛋白质纯化组，先进的诊断公司，拥有用于开发诊断抗体的噬菌体展示平台技术。在Ansata Therapeutics，毛博士发明了基于分选酶的新型酶促蛋白质结合方法，该方法已经获得了研究应用，用于细胞表面标记，蛋白质阵列，核磁共振和蛋白质 – 药物结合等。毛医生进行了她的博士后诺华研究基金会（GNF）雅培实验室和基因组研究所的研究。她在麻省理工学院获得生物化学博士学位，在北京大学获得化学学士学位。毛在诺华研究基金会（GNF）的雅培实验室和基因组研究所进行了博士后研究。她在麻省理工学院获得生物化学博士学位，在北京大学获得化学学士学位。毛在诺华研究基金会（GNF）的雅培实验室和基因组研究所进行了博士后研究。她在麻省理工学院获得生物化学博士学位，在北京大学获得化学学士学位。
Moradec Fab-αHFc-NC-MMAF说明书
Fab-αHFc-NC-MMAF
FAB-αHFc-NC-MMAF
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具有不可切割接头的Fab抗人IgG Fc-MMAF抗体
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目录编号：AH-201-AF
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Fab-αHFc-NC-MMAF是与具有不可切割接头的单甲基auristatin F（MMAF）缀合的抗人IgG Fc特异性抗体的Fab片段。抗体部分是对人IgG的Fc区特异的多克隆抗体Fab片段。单甲基auristatin F（MMAF）是一种细胞毒性小分子，通过阻断微管蛋白的聚合来抑制细胞分裂。连接MMAF与抗体的不可切割接头在细胞外液中是稳定的，但是在进入细胞时可以通过未的机制切割。Fab 2°ADC的单价性质在某些应用中可能比全长IgG 2°ADC具有一些优势。
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二抗 – 药物偶联物目录
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Moradec的新型二抗 – 药物偶联物（2°ADC）是预先筛选抗体导联作为ADC候选物的重要研究工具。“他们工作非常出色，而且没有主要的ab，它们的毒性极低！
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具有可切割接头的IgGs抗人IgG Fc-PBD抗体
具有可切割接头的IgGs抗小鼠IgG Fc-PBD抗体
具有可切割接头的IgG抗兔IgG（H + L）-PBD抗体
Anti-Human IgG (Fc Specific)
IgGs Anti-Human IgG (Fc Specific) ADCs
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Product Name
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Description
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Catalog No
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QTY
|
Price
|
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αHFc-NC-MMAF
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IgGs Anti-Human IgG Fc-MMAF Antibody with Non-Cleavable Linker
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AH-101AF-50
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50µg
|
$330
|
|
AH-101AF-20
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20µg
|
$165
|
|
αHFc-CL-MMAF
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IgGs Anti-Human IgG Fc-MMAF Antibody with Cleavable Linker
|
AH-102AF-50
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50µg
|
$330
|
|
AH-102AF-20
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20µg
|
$165
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|
αHFc-CL-MMAE
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IgGs Anti-Human IgG Fc-MMAE Antibody with Cleavable Linker
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AH-102AE-50
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50µg
|
$330
|
|
AH-102AE-20
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20µg
|
$165
|
|
αHFc-CL-DMSA
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IgGs Anti-Human IgG Fc-Duocarmycin SA Antibody with Cleavable Linker
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AH-102DS-50
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50µg
|
$330
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AH-102DS-20
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20µg
|
$165
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αHFc-CL-DMDM
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IgGs Anti-Human IgG Fc-Duocarmycin DM Antibody with Cleavable Linker
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AH-102DD-50
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50µg
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$330
|
|
AH-102DD-20
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20µg
|
$165
|
|
αHFc-CL-PNU
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IgGs Anti-Human IgG Fc-PNU159682 Antibody with Cleavable Linker
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AH-102PN-50
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50µg
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$330
|
|
AH-102PN-20
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20µg
|
$165
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αHFc-NC-DM1
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IgGs Anti-Human IgG Fc-DM1 Antibody with Non-Cleavable Linker
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AH-103D1-50
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50µg
|
$330
|
|
AH-103D1-20
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20µg
|
$165
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αHFc-CL-PBD
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IgGs Anti-Human IgG Fc-PBD Antibody with Cleavable Linker
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AH-106PB-50
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50µg
|
$330
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AH-106PB-20
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20µg
|
$165
|
Fab Fragments of Anti-Human IgG (Fc Specific) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
Fab-αHFc-NC-MMAF
|
Fab Anti-Human IgG Fc-MMAF Antibody with Non-Cleavable Linker
|
AH-201AF-50
|
50µg
|
$440
|
|
AH-201AF-20
|
20µg
|
$220
|
|
Fab-αHFc-CL-MMAF
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Fab Anti-Human IgG Fc-MMAF Antibody with Cleavable Linker
|
AH-202AF-50
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50µg
|
$440
|
|
AH-202AF-20
|
20µg
|
$220
|
|
Fab-αHFc-CL-MMAE
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Fab Anti-Human IgG Fc-MMAE Antibody with Cleavable Linker
|
AH-202AE-50
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50µg
|
$440
|
|
AH-202AE-20
|
20µg
|
$220
|
|
Fab-αHFc-CL-DMSA
|
Fab Anti-Human IgG Fc-Duocarmycin SA Antibody with Cleavable Linker
|
AH-202DS-50
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50µg
|
$440
|
|
AH-202DS-20
|
20µg
|
$220
|
|
Fab-αHFc-CL-DMDM
|
Fab Anti-Human IgG Fc-Duocarmycin DM Antibody with Cleavable Linker
|
AH-202DD-50
|
50µg
|
$440
|
|
AH-202DD-20
|
20µg
|
$220
|
|
Fab-αHFc-CL-PNU
|
Fab Anti-Human IgG Fc-PNU159682 Antibody with Cleavable Linker
|
AH-202PN-50
|
50µg
|
$440
|
|
AH-202PN-20
|
20µg
|
$220
|
|
Fab-αHFc-NC-DM1
|
Fab Anti-Human IgG Fc-DM1 Antibody with Non-Cleavable Linker
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AH-203D1-50
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50µg
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$440
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AH-203D1-20
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20µg
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$220
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Fab-αHFc-NC-AAMT
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Fab Anti-Human IgG Fc-Amanitin Antibody with Non-Cleavable Linker
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AH-20M-50
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50µg
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$440
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AH-20M-20
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20µg
|
$220
|
Anti-Human IgG (Fab Specific)
IgGs Anti-Human IgG (Fab Specific) ADCs
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Product Name
|
Description
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Catalog No
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QTY
|
Price
|
|
αHFab-NC-MMAF
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IgGs Anti-Human IgG Fab-MMAF Antibody with Nonceavable Linker
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AH-121AF-50
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50µg
|
$360
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AH-121AF-20
|
20µg
|
$180
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αHFab-CL-MMAF
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IgGs Anti-Human IgG Fab-MMAF Antibody with Cleavable Linker
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AH-122AF-50
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50µg
|
$360
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|
AH-122AF-20
|
20µg
|
$180
|
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αHFab-CL-MMAE
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IgGs Anti-Human IgG Fab-MMAE Antibody with Cleavable Linker
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AH-122AE-50
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50µg
|
$360
|
|
AH-122AE-20
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20µg
|
$180
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αHFab-NC-DM1
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IgGs Anti-Human IgG Fab-DM1 Antibody with Non-Cleavable Linker
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AH-123D1-50
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50µg
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$360
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AH-123D1-20
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20µg
|
$180
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Anti-Mouse IgG (Fc Specific)
IgGs Anti-Mouse IgG (Fc specific) ADCs
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Product Name
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Description
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Catalog No
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QTY
|
Price
|
|
αMFc-NC-MMAF
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IgGs Anti-Mouse IgG Fc-MMAF Antibody with Non-Cleavable Linker
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AM-101AF-50
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50µg
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$374
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AM-101AF-20
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20µg
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$187
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αMFc-CL-MMAF
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IgGs Anti-Mouse IgG Fc-MMAF Antibody with Cleavable Linker
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AM-102AF-50
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50µg
|
$374
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|
AM-102AF-20
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20µg
|
$187
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|
αMFc-CL-MMAE
|
IgGs Anti-Mouse IgG Fc-MMAE Antibody with Cleavable Linker
|
AM-102AE-50
|
50µg
|
$374
|
|
AM-102AE-20
|
20µg
|
$187
|
|
αMFc-CL-DMSA
|
IgGs Anti-Mouse IgG Fc-Duocarmycin SA Antibody with Cleavable Linker
|
AM-102DS-50
|
50µg
|
$374
|
|
AM-102DS-20
|
20µg
|
$187
|
|
αMFc-CL-DMDM
|
IgGs Anti-Mouse IgG Fc-Duocarmycin DM Antibody with Cleavable Linker
|
AM-102DD-50
|
50µg
|
$374
|
|
AM-102DD-20
|
20µg
|
$187
|
|
αMFc-CL-PNU
|
IgGs Anti-Mouse IgG Fc-PNU159682 Antibody with Cleavable Linker
|
AM-102PN-50
|
50µg
|
$374
|
|
AM-102PN-20
|
20µg
|
$187
|
|
αMFc-NC-DM1
|
IgGs Anti-Mouse IgG Fc-DM1 Antibody with Non-Cleavable Linker
|
AM-103D1-50
|
50µg
|
$374
|
|
AM-103D1-20
|
20µg
|
$187
|
|
αMFc-CL-PBD
|
IgGs Anti-Mouse IgG Fc-PBD Antibody with Cleavable Linker
|
AM-106PB-50
|
50µg
|
$374
|
|
AM-106PB-20
|
20µg
|
$187
|
Fab Fragments of Anti-Mouse IgG (Fc Specific) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
Fab-αMFc-NC-MMAF
|
Fab Anti-Mouse IgG Fc-MMAF Antibody with Non-Cleavable Linker
|
AM-201AF-50
|
50µg
|
$495
|
|
AM-201AF-20
|
20µg
|
$248
|
|
Fab-αMFc-CL-MMAF
|
Fab Anti-Mouse IgG Fc-MMAF Antibody with Cleavable Linker
|
AM-202AF-50
|
50µg
|
$495
|
|
AM-202AF-20
|
20µg
|
$248
|
|
Fab-αMFc-CL-MMAE
|
Fab Anti-Mouse IgG Fc-MMAE Antibody with Cleavable Linker
|
AM-202AE-50
|
50µg
|
$495
|
|
AM-202AE-20
|
20µg
|
$248
|
|
Fab-αMFc-CL-DMDM
|
Fab Anti-Mouse IgG Fc-duocarmycin DM Antibody with Cleavable Linker
|
AM-202DD-50
|
50µg
|
$495
|
|
AM-202DD-20
|
20µg
|
$248
|
|
Fab-αMFc-NC-DM1
|
Fab Anti-Mouse IgG Fc-DM1 Antibody with Noncleavable Linker
|
AM-203D1-50
|
50µg
|
$495
|
|
AM-203D1-20
|
20µg
|
$248
|
Anti-Rabbit IgG (Fc Specific)
IgGs Anti-Rabbit IgG (Fc Specific) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
αOFc-NC-MMAF
|
IgGs Anti-Rabbit IgG Fc-MMAF Antibody with Non-Cleavable Linker
|
AO-101AF-50
|
50µg
|
$396
|
|
AO-101AF-20
|
20µg
|
$198
|
Fab Fragments of Anti-Rabbit IgG (Fc Specific) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
Fab-αOFc-NC-MMAF
|
Fab Anti-Rabbit IgG Fc-MMAF Antibody with Non-Cleavable Linker
|
AO-201AF-50
|
50µg
|
$528
|
|
AO-201AF-20
|
20µg
|
$264
|
Anti-Rabbit IgG(H+L)
IgGs Anti-Rabbit IgG (H+L) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
αOIgG-NC-MMAF
|
IgGs Anti-Rabbit IgG(H+L)-MMAF Antibody with Non-Cleavable Linker
|
AO-111AF-50
|
50µg
|
$396
|
|
AO-111AF-20
|
20µg
|
$198
|
|
αOIgG-CL-MMAF
|
IgGs Anti-Rabbit IgG(H+L)-MMAF Antibody with Cleavable Linker
|
AO-112AF-50
|
50µg
|
$396
|
|
AO-112AF-20
|
20µg
|
$198
|
|
αOIgG-CL-MMAE
|
IgGs Anti-Rabbit IgG(H+L)-MMAE Antibody with Cleavable Linker
|
AO-112AE-50
|
50µg
|
$396
|
|
AO-112AE-20
|
20µg
|
$198
|
|
αOIgG-CL-PBD
|
IgGs Anti-Rabbit IgG(H+L)-PBD Antibody with Cleavable Linker
|
AO-116PB-50
|
50µg
|
$396
|
|
AO-116PB-20
|
20µg
|
$198
|
Fab Fragments of Anti-Rabbit IgG (H+L) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
Fab-αOIgG-NC-MMAF
|
Fab Anti-Rabbit IgG(H+L)-MMAF Antibody with Non-Cleavable Linker
|
AO-211AF-50
|
50µg
|
$528
|
|
AO-211AF-20
|
20µg
|
$264
|
|
Fab-αOIgG-CL-MMAF
|
Fab Anti-Rabbit IgG(H+L)-MMAF Antibody with Cleavable Linker
|
AO-212AF-50
|
50µg
|
$528
|
|
AO-212AF-20
|
20µg
|
$264
|
Anti-Rat IgG(Fc Specific)
IgGs Anti-Rat IgG (Fc Specific) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
αRFc-NC-MMAF
|
IgGs Anti-Rat IgG Fc-MMAF Antibody with Non-Cleavable Linker
|
AR-101AF-50
|
50µg
|
$396
|
|
AR-101AF-20
|
20µg
|
$198
|
|
αRFc-CL-MMAF
|
IgGs Anti-Rat IgG Fc-MMAF Antibody with Cleavable Linker
|
AR-102AF-50
|
50µg
|
$396
|
|
AR-102AF-20
|
20µg
|
$198
|
Fab Fragments of Anti-Rat IgG (Fc Specific) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
Fab-αRFc-NC-MMAF
|
Fab Anti-Rat IgG Fc-MMAF Antibody with Non-Cleavable Linker
|
AR-201AF-50
|
50µg
|
$528
|
|
AR-201AF-20
|
20µg
|
$264
|
|
Fab-αRFc-CL-MMAF
|
Fab Anti-Rat IgG Fc-MMAF Antibody with Cleavable Linker
|
AR-202AF-50
|
50µg
|
$528
|
|
AR-202AF-20
|
20µg
|
$264
|
|
Fab-αRFc-CL-MMAE
|
Fab Anti-Rat IgG Fc-MMAE Antibody with Cleavable Linker
|
AR-202AE-50
|
50µg
|
$528
|
|
AR-202AE-20
|
20µg
|
$264
|
|
Fab-αRFc-CL-DMDM
|
Fab Anti-Rat IgG Fc-Duocarmycin DM Antibody with Cleavable Linker
|
AR-202DD-50
|
50µg
|
$528
|
|
AR-202DD-20
|
20µg
|
$264
|
Anti-Rat IgG(H+L)
IgGs Anti-Rat IgG (H+L) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
αRIgG-NC-MMAF
|
IgGs Anti-Rat IgG(H+L)-MMAF Antibody with Non-Cleavable Linker
|
AR-111AF-50
|
50µg
|
$396
|
|
AR-111AF-20
|
20µg
|
$198
|
Fab Fragments of Anti-Rat IgG (H+L) ADCs
|
Product Name
|
Description
|
Catalog No
|
QTY
|
Price
|
|
Fab-αRIgG-NC-MMAF
|
Fab Anti-Rat IgG(H+L)-MMAF Antibody with Non-Cleavable Linker
|
AR-211AF-50
|
50µg
|
$528
|
|
AR-211AF-20
|
20µg
|
$264
|
|
Fab-αRIgG-CL-MMAF
|
Fab Anti-Rat IgG(H+L)-MMAF Antibody with Cleavable Linker
|
AR-212AF-50
|
50µg
|
$528
|
|
AR-212AF-20
|
20µg
|
$264
|
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上海金畔生物科技有限公司是实验试剂一站式采购服务商
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3：提供加急服务，货品一般1-2周到货。
4：富有竞争力的价格优势，绝大部分价格有优势。
5：多年积累良好的信誉，大部分客户提供货到付款服务。客户包括清华、北大、交大、复旦、中山等100多所高校，ROCHE，阿斯利康、国药、fisher等药企。
6：我们还是Santa,Advanced Biotechnologies Inc,Athens Research & Technology,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, Genebridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech；sysy,TriLink BioTechnologies,Inc；worthington-biochem,zyagen等几十家国外公司代理。
7：我们还是invitrogen,qiagen,MiraiBioam,sigma;neb,roche,merck, rnd,BD, GE,pierce,BioLegend等*批发，欢迎合作。
