BioPorto ABS 033-10B-005 说明书
上海金畔生物专业代理并分销BioPorto糖尿病、肥胖症等代谢疾病相关的单克隆抗体。蛋白质/多肽类激素通常是产生于特定刺激后分泌到循环系统中的激素原，一旦分泌，大多数的肽激素在血液循环自由存在。在穿越血液循环的同时，在靶细胞表面遇到受体，并与特定的内分泌细胞上的细胞表面受体结合。内分泌细胞合成，储存和分泌蛋白质/多肽激素，并再次激活各种信号转导系统，内分泌的紊乱会引起多种代谢疾病。
糖尿病相关
胰高血糖素样肽-1(GLP-1) 存在多种剪切体，包括GLP-1 Extended form、GLP-1 Active form及GLP-1 Metabolite等。BioPorto专业提供针对各种形式GLP-1的单克隆抗体，用于GLP-1糖尿病治疗的研究及检测，为早期研发阶段、临床阶段I和/或在zui终治疗产品的生产和质量控制过程提供可靠依据。
图1 不同形式的GLP-1 (Glucagon-likepeptide1)示意图
提供胰高血糖素样肽-2(GLP-2)、胰多肽(PP)、Exendin-4、胰高血糖素（Glucagon）等糖尿病研究相关单克隆抗体：
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货号
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产品名称
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规格
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宿主
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应用
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ABS 033-04-02
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Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)
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200µl
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Mouse
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ELISA, IHC
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ABS 033-04-1
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Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)
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1ml
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Mouse
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ELISA, IHC
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ABS 033-10-02
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Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)
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200µl
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Mouse
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ELISA, WB
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ABS 033-10-1
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Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)
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1ml
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Mouse
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ELISA, WB
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ABS 033-10B-005
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Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)
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50µl
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Mouse
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ELISA
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ABS 044-49-02
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Glucagon-like peptide-1 (GLP-1(9-37) and GLP-1(9-36)amide, N-terminal specific)
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200µl
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Mouse
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ELISA, WB
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ABS 044-49-1
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Glucagon-like peptide-1 (GLP-1(9-37) and GLP-1(9-36)amide, N-terminal specific)
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1ml
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Mouse
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ELISA, WB
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ABS 044-53-02
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Glucagon-like peptide-1 (GLP-1(9-37) and GLP-1(9-36)amide, N-terminal specific)
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200µl
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Mouse
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ELISA, WB
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ABS 044-53-1
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Glucagon-like peptide-1 (GLP-1(9-37) and GLP-1(9-36)amide, N-terminal specific)
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1ml
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Mouse
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ELISA, WB
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ABS 046-03-02
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Glucagon-like peptide-1 (GLP-1, Non-amidated (-Arg-Gly), C-terminal specific)
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200µl
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Mouse
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ELISA, WB
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ABS 046-03-1
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Glucagon-like peptide-1 (GLP-1, Non-amidated (-Arg-Gly), C-terminal specific)
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1ml
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Mouse
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ELISA, WB
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ABS 046-03B-005
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Glucagon-like peptide-1 (GLP-1, Non-amidated (-Arg-Gly), C-terminal specific)
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50µl
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Mouse
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ELISA
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HYB 011-05-02
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Glucagon-like peptide-1 (GLP-1(1-36)amide, N-terminal-extension specific)
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200µl
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Mouse
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ELISA, WB
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HYB 011-05-1
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Glucagon-like peptide-1 (GLP-1(1-36)amide, N-terminal-extension specific)
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1ml
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Mouse
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ELISA, WB
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HYB 147-06-02
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Glucagon-like peptide-1 (GLP-1 (7-36)amide, C-terminal specific)
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200µl
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Mouse
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ELISA, IHC
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HYB 147-06-1
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Glucagon-like peptide-1 (GLP-1 (7-36)amide, C-terminal specific)
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1ml
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Mouse
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ELISA, IHC
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HYB 147-06B-005
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Glucagon-like peptide-1 (GLP-1 (7-36)amide, C-terminal specific)
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50µl
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Mouse
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ELISA
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HYB 147-08-02
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Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)
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200µl
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Mouse
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ELISA, WB
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HYB 147-08-1
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Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)
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1ml
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Mouse
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ELISA, WB
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HYB 147-08B-005
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Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)
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50µl
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Mouse
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ELISA
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HYB 147-12-02
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Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)
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200µl
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Mouse
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ELISA, WB, IHC
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HYB 147-12-1
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Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)
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1ml
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Mouse
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ELISA, WB, IHC
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HYB 147-12B-005
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Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)
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50µl
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Mouse
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ELISA
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HYB 147-13-02
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Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)
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200µl
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Mouse
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ELISA, WB
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HYB 147-13-1
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Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)
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1ml
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Mouse
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ELISA, WB
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HYB 006-02-02
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Glucagon-like peptide-2 (human, GLP-2)
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200µl
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Mouse
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ELISA
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HYB 006-02-1
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Glucagon-like peptide-2 (human, GLP-2)
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1ml
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Mouse
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ELISA
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ABS 030-06-02
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Pancreatic Polypeptide (human, PP)
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200µl
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Mouse
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ELISA, WB
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ABS 030-06-1
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Pancreatic Polypeptide (human, PP)
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1ml
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Mouse
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ELISA, WB
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HYB 347-06-02
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Pancreatic PolyPeptide (PP)
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200µL
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Mouse
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ELISA
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HYB 347-06-1
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Pancreatic PolyPeptide (PP)
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1ml
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Mouse
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ELISA
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ABS 012-20-02
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Exendin-4
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200µl
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Mouse
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ELISA
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ABS 012-20-1
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Exendin-4
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1ml
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Mouse
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ELISA
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ABS 012-24-02
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Exendin-4
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200µl
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Mouse
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ELISA
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ABS 012-24-1
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Exendin-4
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1ml
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Mouse
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ELISA
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ABS 012-35-02
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Exendin-4
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200µl
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Mouse
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ELISA
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ABS 012-35-1
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Exendin-4
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1ml
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Mouse
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ELISA
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ABS 012-35B-005
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Exendin-4
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50µl
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Mouse
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ELISA
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ABS 058-08-02
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Glucagon (human, pig, rat)
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200µl
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Mouse
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ELISA
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ABS 058-08-1
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Glucagon (human, pig, rat)
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1ml
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Mouse
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ELISA
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ABS 058-08B-005
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Glucagon (human, pig, rat)
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50µl
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Mouse
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ELISA
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ABS 061-09-02
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Glucagon (human, pig, rat)
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200µl
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Mouse
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ELISA
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ABS 061-09-1
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Glucagon (human, pig, rat)
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1ml
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Mouse
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ELISA
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Anti-GLP-1(7-37) and GLP-1(7-36)amide (N-terminal specific)
CAT.NO. ABS 033-10B
DELIVERY: 1-5 DAYS
Cat. No.
ABS 033-10B
Product name
Anti-GLP-1(7-37) and GLP-1(7-36)amide (N-terminal specific)
Description
Mouse monoclonal antibody, biotinylated
Specificity
ABS 033-10 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximay 6% with human GLP-2 and approximay 50% with exendin-4. ABS 033-10 cross-reacts with Liraglutide.聽
Immunogen
Synthetic GLP-1(7-17)聽
Application
ELISA
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass
IgG2a/k
Gene ID
2641
Clone number
10
Epitope
Free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide.
Content
50 碌L, 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Biotinylated
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
