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| 名称 | [Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human |
| 编码 | |
| 别名 | [Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human |
| 纯度 | 80%，90%，95%，98%，99% |
| 重量 | 1mg,5mg,10mg,50mg,100mg,1g |
| 序列（单字母缩写） | Biotin-KGGHLKSK-K(Ac)-GQSTSRHKKLMFKTEGPDSD-NH2 |
| 序列（三字母缩写） | Biotin-Lys-Gly-Gly-His-Leu-Lys-Ser-Lys-Lys(Ac)-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2(trifluoroacetate salt) |
| 基本描述 | This is a biotin-labeled and amidated peptide derived from residues 368-393 of human p53 tumor suppressor protein with acetylation at Lys373 and additional KGW residues on its N-terminus. Activated p53 functions to induce cell cycle arrest and apoptosis in response to signals such as DNA damage. Acetylation of p53 reduces ubiquitination by MDM2 and increases p53 half-life in vivo. |
| 溶解度 | |
| 分子量 | 3481 |
| 化学式 | |
| 存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| 注释 | |
| Documents | ![[Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human 编码](http://www.saliva.com.cn/wp-content/uploads/2022/10/20221005_633d89a2c5b6c.png) |
| Figures | ![[Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human 编码](http://www.saliva.com.cn/wp-content/uploads/2022/10/20221005_633d89a3237a9.jpg) |
| Reference | Kanovsky, M. et al. Proc Natl Acad Sci 98, 12438 (2001) |
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