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| 名称 | Acetyl-(D-Trp1,D-Phe(4-Cl)2,D-Trp3,D-Arg6,D-Ala10)-LHRH |
| 编码 | [86044-76-0] |
| 别名 | Acetyl-(D-Trp1,D-Phe(4-Cl)2,D-Trp3,D-Arg6,D-Ala10)-LHRH |
| 纯度 | 80%，90%，95%，98%，99% |
| 重量 | 1mg,5mg,10mg,50mg,100mg,1g |
| 序列（单字母缩写） | Ac-w-chloro-fwSYrLRPa-NH2 |
| 序列（三字母缩写） | Ac-D-Trp-4-chloro-D-Phe-D-Trp-Ser-Tyr-D-Arg-Leu-Arg-Pro-D-Ala-NH2?(trifluoroacetate salt) |
| 基本描述 | As a potent LHRH agonist, histrelin stimulates LH and FSH release and inhibits the actions of sex steroids on the male and female reproductive tracts. Its potency in vivo and in vitro is similar to that of the D-Trp6-containing analog. Especially because of its high water solubility and greater lipophilic character, histrelin appears promising for clinical application.Slow-release implants containing histreline implants were approved for the palliative treatment of advanced hormone-dependent prostate cancer. |
| 溶解度 | |
| 分子量 | 1457.1 |
| 化学式 | C55H75N17O13 |
| 存储条件 | Store at -20°C. Keep tightly closed. Store in a cool dry place. |
| 注释 | |
| Documents | ![Acetyl-(D-Trp1,D-Phe(4-Cl)2,D-Trp3,D-Arg6,D-Ala10)-LHRH 编码 [86044-76-0]](http://www.saliva.com.cn/wp-content/uploads/2022/10/20221005_633d7f1c9740f.png) |
| Figures | ![Acetyl-(D-Trp1,D-Phe(4-Cl)2,D-Trp3,D-Arg6,D-Ala10)-LHRH 编码 [86044-76-0]](http://www.saliva.com.cn/wp-content/uploads/2022/10/20221005_633d7f1ceb614.jpg) |
| Reference | S.E.Kirk et al., Endocrinology, 135, 876 (1994) A.C.Dalkin et al., Endocrinology, 139, 2818 (1998) L.L.Burger et al., Endocrinology, 142, 3435 (2001) K.A.Prendergast et al., Biol. Reprod., 70, 364 (2004) |
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