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名称	Uroguanylin, human
编码	[154525-25-4]
别名	Uroguanylin, human
纯度	80%，90%，95%，98%，99%
重量	1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写）	NDDCELCVNVACTGCL (C4&C12 bridge, C7&C15 bridge)
序列（三字母缩写）	H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH (trifluoroacetate salt)(Cys4 and 12 bridge, Cys7 and 15 bridge)
基本描述	A HCV protease substrate that incoporates an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM. Upon cleavage of this substrate, fluorescence can be monitored at Abs/Em = 355/500 nm. As an internally quenced fluorogenic substrate, it can be used to monitor HCV NS3 protease activity.
溶解度
分子量	1667.9
化学式	C64H102N18O26S4
存储条件	Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents
Figures
Reference	T. Kita et al., Am. J. Physiol., 266, F342 (1994)
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化学桥	(Cys4 and 12 bridge, Cys7 and 15 bridge)